STRING 9.05 






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This is the confidence view. Stronger associations are represented by thicker lines.

 
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Your Input:
NR1I3
nuclear receptor subfamily 1, group I, member 3; Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (357 aa)
(Homo sapiens)
Predicted Functional Partners:
RXRA
retinoid X receptor, alpha; Nuclear hormone receptor. Involved in the retinoic acid response pa [...] (462 aa)
0.963
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4; Cytochromes P450 are a group of heme-thi [...] (503 aa)
0.953
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6; Cytochromes P450 are a group of heme-thi [...] (491 aa)
0.947
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1; UDPGT is of major importance in the conju [...] (533 aa)
0.927
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1 (504 aa)
0.916
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1; Energy-dependent efflux pump responsibl [...] (1280 aa)
0.906
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8; Cytochromes P450 are a group of heme-thi [...] (490 aa)
0.902
EGFL8
EGF-like-domain, multiple 8 (293 aa)
0.899
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A5; UDPGT is of major importance in the conju [...] (534 aa)
0.897
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; Cat [...] (285 aa)
0.886
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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