STRING 9.05 






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This is the evidence view. Different line colors represent the types of evidence for the association.

 
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Your Input:
RARA
retinoic acid receptor, alpha; This is a receptor for retinoic acid. Retinoic acid has profound effects on vertebrate development, is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing MLL5. Mediates retinoic acid-induced granulopoiesis (462 aa)
(Homo sapiens)
Predicted Functional Partners:
RXRA
retinoid X receptor, alpha; Nuclear hormone receptor. Involved in the retinoic acid response pa [...] (462 aa)
    0.999
PML
promyelocytic leukemia; Probable transcription factor. May play an important role in recruitmen [...] (882 aa)
     0.999
NCOR1
nuclear receptor co-repressor 1; Mediates transcriptional repression by certain nuclear recepto [...] (2440 aa)
      0.999
NCOA1
nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear recept [...] (1441 aa)
      0.999
NCOR2
nuclear receptor co-repressor 2; Mediates the transcriptional repression activity of some nucle [...] (2521 aa)
      0.998
NRIP1
nuclear receptor interacting protein 1; Modulates transcriptional activation by steroid recepto [...] (1158 aa)
      0.998
NCOA3
nuclear receptor coactivator 3; Nuclear receptor coactivator that directly binds nuclear recept [...] (1424 aa)
      0.996
PRKCA
protein kinase C, alpha; This is a calcium-activated, phospholipid-dependent, serine- and threo [...] (672 aa)
     0.992
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
      0.990
NR0B2
nuclear receptor subfamily 0, group B, member 2; Acts as a negative regulator of receptor-depen [...] (257 aa)
      0.983
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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