Your Input: |
 | PPARD | peroxisome proliferator-activated receptor delta; Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand (441 aa) |
| | (Homo sapiens) |
Predicted Functional Partners: |
 | CREBBP | CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa) | | | | | | • | • | | 0.925 |
 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa; Involved in the regulation of cell adhesi [...] (781 aa) | | | | | | • | • | | 0.911 |
 | ESR1 | estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are inv [...] (595 aa) | | | | | | • | • | • | 0.908 |
 | RXRA | retinoid X receptor, alpha; Nuclear hormone receptor. Involved in the retinoic acid response pa [...] (462 aa) | | | | | | • | • | • | 0.907 |
 | HNF4A | hepatocyte nuclear factor 4, alpha; Transcriptionally controlled transcription factor. Binds to [...] (474 aa) | | | | | | • | • | • | 0.904 |
 | RXRG | retinoid X receptor, gamma; Nuclear hormone receptor. Involved in the retinoic acid response pa [...] (463 aa) | | | | | | • | • | • | 0.904 |
 | ESRRA | estrogen-related receptor alpha; Binds to an ERR-alpha response element (ERRE) containing a sin [...] (423 aa) | | | | | | • | • | • | 0.904 |
 | THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avia [...] (490 aa) | | | | | | • | • | • | 0.903 |
 | PPARG | peroxisome proliferator-activated receptor gamma; Receptor that binds peroxisome proliferators [...] (505 aa) | | | | | | • | • | • | 0.903 |
 | VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor; Nuclear hormone receptor. Transcription factor [...] (427 aa) | | | | | | • | • | • | 0.903 |