STRING 9.05 






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This is the confidence view. Stronger associations are represented by thicker lines.

 
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Your Input:
PGR
progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation (933 aa)
(Homo sapiens)
Predicted Functional Partners:
NCOA1
nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear recept [...] (1441 aa)
0.993
NCOA3
nuclear receptor coactivator 3; Nuclear receptor coactivator that directly binds nuclear recept [...] (1424 aa)
0.985
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
0.983
SP1
Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)
0.980
CCND1
cyclin D1; Essential for the control of the cell cycle at the G1/S (start) transition (295 aa)
0.970
JDP2
Jun dimerization protein 2; Component of the AP-1 transcription factor that represses transacti [...] (174 aa)
0.958
NCOR2
nuclear receptor co-repressor 2; Mediates the transcriptional repression activity of some nucle [...] (2521 aa)
0.953
CDK2
cyclin-dependent kinase 2; Involved in the control of the cell cycle. Interacts with cyclins A, [...] (298 aa)
0.953
ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene [...] (1255 aa)
0.946
KLF9
Kruppel-like factor 9; Transcription factor that binds to GC box promoter elements. Selectively [...] (244 aa)
0.940
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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