STRING 9.05 






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This is the confidence view. Stronger associations are represented by thicker lines.

 
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Your Input:
AR
androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 (920 aa)
(Homo sapiens)
Predicted Functional Partners:
NCOA1
nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear recept [...] (1441 aa)
0.999
NCOA2
nuclear receptor coactivator 2; Transcriptional coactivator for steroid receptors and nuclear r [...] (1464 aa)
0.999
KLK3
kallikrein-related peptidase 3; Hydrolyzes semenogelin-1 thus leading to the liquefaction of th [...] (261 aa)
0.999
NCOR1
nuclear receptor co-repressor 1; Mediates transcriptional repression by certain nuclear recepto [...] (2440 aa)
0.999
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa; Involved in the regulation of cell adhesi [...] (781 aa)
0.999
NCOA4
nuclear receptor coactivator 4; Enhances the androgen receptor transcriptional activity in pros [...] (650 aa)
0.999
UBC
ubiquitin C (685 aa)
0.999
NCOR2
nuclear receptor co-repressor 2; Mediates the transcriptional repression activity of some nucle [...] (2521 aa)
0.998
NCOA3
nuclear receptor coactivator 3; Nuclear receptor coactivator that directly binds nuclear recept [...] (1424 aa)
0.997
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
0.997
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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