STRING 9.05 






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This is the confidence view. Stronger associations are represented by thicker lines.

 
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Your Input:
ESRRG
estrogen-related receptor gamma; Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity) (458 aa)
(Homo sapiens)
Predicted Functional Partners:
NR0B2
nuclear receptor subfamily 0, group B, member 2; Acts as a negative regulator of receptor-depen [...] (257 aa)
0.994
ESRRA
estrogen-related receptor alpha; Binds to an ERR-alpha response element (ERRE) containing a sin [...] (423 aa)
0.993
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; Transcriptional coactiva [...] (798 aa)
0.983
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta; Plays a role of stimulato [...] (1023 aa)
0.954
PPARA
peroxisome proliferator-activated receptor alpha; Ligand-activated transcription factor. Key re [...] (468 aa)
0.907
PPARG
peroxisome proliferator-activated receptor gamma; Receptor that binds peroxisome proliferators [...] (505 aa)
0.906
ESR1
estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are inv [...] (595 aa)
0.906
ESR2
estrogen receptor 2 (ER beta); Nuclear hormone receptor. Binds estrogens with an affinity simil [...] (530 aa)
0.904
NR2C1
nuclear receptor subfamily 2, group C, member 1; Orphan nuclear receptor. Represses transcripti [...] (603 aa)
0.903
NR2C2
nuclear receptor subfamily 2, group C, member 2; Orphan nuclear receptor. May regulate gene exp [...] (615 aa)
0.903
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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